Hop into a moto-taxi and if they don't know 'Tambopata Hostel', or 'avenida 26 de deciembre', just ask for the Plaza de Armas (main city sq.); stick with it previous the most crucial sq. on the right hand facet, and on achieving the top corner request the driver to show proper (derecha) and continue nearly the last highway (avenida 26 de deciembre)